研究生 students showcase leading-edge re搜索 during awards competition

实验室里的学生

研究生 students presented their re搜索 during the annual 研究生 and Professional Student 研究 and Awards Showcase

博彩平台网址大全 students presented projects on leading-edge re搜索 ranging from an analysis of proteins used to treat cancer and a study that analyzed music playlists to treat anxiety during the annual 研究生 and Professional Student 研究 and Awards Showcase.

"These presentations are a result of the grit and persistence of our students to continue their re搜索, despite the pandemic and all the barriers that it has presented,Cyd Jenefsky说, vice provost and interim dean of the graduate school. "We are proud of our students for producing re搜索 that benefits the Pacific community and society as a whole."

Students presented their re搜索 during the Three Minute 研究 and 研究 Poster Competitions, judged by a panel of faculty on both the quality of their work and presentation. Winners received cash prizes.

Judges for the showcase were: Rick Hutley, data science; Joan Lin-Cereghino, biology; Mike McCallum, 化学; Delores McNair, education; and Balint Sztaray, 化学.

Two highlights of this year’s showcase included:

Anneroos Nederstigt, bio化学 doctoral candidate
研究: The ubiquitination cascade: scoring touchdowns...在你的身体里

Bio化学 student Anneroos Nederstigt won first place for her project that analyzed how specific proteins can be used to treat several diseases. She used the Super Bowl Champion Tampa Bay Buccaneers to help explain the “ubiquitination cascade,” a pathway in humans for proteins to be labeled with the molecule ubiquitin.

Ubiquitin is a small protein that is present in all eukaryotic cells, which are complex cells that contain a nucleus and other areas of specialized function, 膜分离. Ubiquitin directs the movement of important proteins in the cell, participating in both the synthesis of new proteins and the destruction of defective proteins.  

Nederstigt's re搜索 focused on using an inhibitor for ubiquitin to manipulate the protein in cancer cells to cause the cancer cell to die.

"I focused on this strategy because the ubiquitination cascade is involved in the development of a plethora of diseases,尼德斯特解释说. "By inhibiting the ubiquitination cascade, I am trying to establish if it is a verifiable therapeutic target to use in treatments for these diseases and also see how the body copes." 
 
Nederstigt hopes her re搜索 will help scientists better understand the process of the ubiquitination cascade and help treat diseases including cervical cancer, Huntington’s and Parkinson’s.

Katie Bautch, music therapy doctoral candidate
研究: The effect of therapeutic music playlists on symptoms of anxiety: a clinical trial

Since the 1940s, music therapists have used multiple strategies to help people manage their emotions. Doctoral student Katie Bautch wanted to dig deeper to determine what kinds of music may be most effective.

"Music has the ability to affect the emotional state of individuals in both a positive and detrimental way,鲍契解释道. "People do not always select music for themselves that will improve their emotional state."

Bautch's study examined the effectiveness of “mood vectoring” playlists—music used to alter a person’s mood by utilizing calming classical music compared to “musical contour regulation” playlists—music that alternates high arousal and low arousal musical experiences that calms a patient and also excites them to determine which is more effective in the treatment of anxiety.

Early results showed the musical contour regulation playlist had a slightly better effect in relieving symptoms of anxiety. Bautch plans to conduct future re搜索 with a larger sample size to further analyze her results.

Bautch hopes this re搜索 will provide patients with a treatment that will offer them long-term improvement and give them the skills to better manage their anxiety.

To see all of the re搜索 presentations and award winners visit the 研究生 and Professional Student 研究 and Awards Showcase website.